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Guang Liang Selected Research

piperlongumine

7/2021Piperlongumine inhibits migration and proliferation of castration-resistant prostate cancer cells via triggering persistent DNA damage.
11/2019Piperlongumine reduces ovalbumin‑induced asthma and airway inflammation by regulating nuclear factor‑κB activation.
1/2019Piperlongumine, a Novel TrxR1 Inhibitor, Induces Apoptosis in Hepatocellular Carcinoma Cells by ROS-Mediated ER Stress.
1/2017Selective Targeting of Cancer Cells by Oxidative Vulnerabilities with Novel Curcumin Analogs.
5/2016Piperlongumine as a direct TrxR1 inhibitor with suppressive activity against gastric cancer.
11/2015Auranofin induces apoptosis by ROS-mediated ER stress and mitochondrial dysfunction and displayed synergistic lethality with piperlongumine in gastric cancer.

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Guang Liang Research Topics

Disease

88Neoplasms (Cancer)
04/2022 - 03/2009
83Inflammation (Inflammations)
10/2022 - 12/2010
54Fibrosis (Cirrhosis)
10/2022 - 06/2014
31Acute Lung Injury
07/2022 - 03/2015
28Stomach Neoplasms (Stomach Cancer)
12/2021 - 03/2015
19Obesity
10/2022 - 02/2015
19Hypertrophy
06/2022 - 01/2013
14Sepsis (Septicemia)
07/2022 - 01/2014
13Hyperglycemia
06/2022 - 06/2014
13Diabetic Nephropathies (Diabetic Nephropathy)
02/2022 - 06/2012
13Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung)
01/2019 - 09/2012
12Diabetic Cardiomyopathies
01/2021 - 01/2013
12Colonic Neoplasms (Colon Cancer)
01/2020 - 06/2015
12Lung Neoplasms (Lung Cancer)
01/2019 - 06/2011
11Wounds and Injuries (Trauma)
05/2021 - 07/2015
10Mitochondrial Diseases (Mitochondrial Disease)
04/2021 - 07/2015
9Body Weight (Weight, Body)
10/2022 - 06/2014
9Non-alcoholic Fatty Liver Disease
10/2022 - 01/2018
8Pancreatic Neoplasms (Pancreatic Cancer)
05/2022 - 06/2015
7Cardiomyopathies (Cardiomyopathy)
10/2022 - 01/2019
7Lung Injury
07/2022 - 08/2015
7Triple Negative Breast Neoplasms
07/2022 - 11/2018
7Carcinoma (Carcinomatosis)
01/2020 - 01/2010
7Type 1 Diabetes Mellitus (Autoimmune Diabetes)
06/2019 - 01/2013
6Atherosclerosis
06/2022 - 07/2009
6Neoplasm Metastasis (Metastasis)
01/2020 - 12/2014
5Heart Failure
10/2022 - 10/2020
5Prostatic Neoplasms (Prostate Cancer)
07/2021 - 05/2009
5Insulin Resistance
01/2018 - 01/2016
4Vascular System Injuries
10/2022 - 09/2019
4Pulmonary Edema
01/2022 - 03/2015
4Liver Cirrhosis (Hepatic Cirrhosis)
09/2021 - 05/2016
4Carcinogenesis
11/2019 - 10/2014
4Diabetes Complications
01/2019 - 01/2013
4Reperfusion Injury
09/2018 - 01/2015
3Cognitive Dysfunction
01/2022 - 01/2016
3Vascular Remodeling
01/2021 - 01/2017
3Hypertension (High Blood Pressure)
12/2020 - 01/2019
3Cardiomegaly (Heart Hypertrophy)
11/2020 - 03/2016
3Cardiovascular Diseases (Cardiovascular Disease)
03/2020 - 03/2016
3Melanoma (Melanoma, Malignant)
01/2020 - 10/2013

Drug/Important Bio-Agent (IBA)

60CurcuminIBA
05/2022 - 03/2009
34Proteins (Proteins, Gene)FDA Link
10/2022 - 06/2014
27CytokinesIBA
07/2022 - 01/2015
26Biological ProductsIBA
07/2022 - 05/2010
21Reactive Oxygen Species (Oxygen Radicals)IBA
04/2021 - 01/2012
18LipopolysaccharidesIBA
07/2022 - 01/2014
17Angiotensin IIIBA
08/2022 - 01/2016
16Pharmaceutical PreparationsIBA
06/2022 - 10/2012
16ErbB Receptors (EGF Receptor)IBA
01/2019 - 01/2016
15Anti-Inflammatory Agents (Anti-Inflammatories)IBA
11/2021 - 06/2012
14Chalcone (Benzalacetophenone)IBA
07/2022 - 01/2015
13LipidsIBA
10/2022 - 01/2016
13Glucose (Dextrose)FDA LinkGeneric
06/2022 - 06/2012
12Toll-Like Receptor 4IBA
01/2022 - 01/2017
10Streptozocin (Streptozotocin)FDA Link
03/2021 - 01/2013
9Palmitic Acid (Hexadecanoic Acid)IBA
06/2022 - 11/2015
9Phosphotransferases (Kinase)IBA
01/2022 - 10/2013
9AntioxidantsIBA
03/2021 - 01/2015
8STAT3 Transcription Factor (Signal Transducer and Activator of Transcription 3)IBA
11/2019 - 06/2015
7Interleukin-6 (Interleukin 6)IBA
05/2022 - 06/2015
7WZ35 compoundIBA
11/2019 - 03/2015
7EnzymesIBA
01/2018 - 05/2009
6Toll-Like Receptors (Toll-Like Receptor)IBA
10/2022 - 01/2014
6SesquiterpenesIBA
06/2022 - 01/2018
6LactonesIBA
06/2022 - 01/2018
6Apolipoproteins E (ApoE)IBA
06/2022 - 04/2016
6piperlongumineIBA
07/2021 - 11/2015
6Antineoplastic Agents (Antineoplastics)IBA
07/2021 - 10/2015
6Insulin (Novolin)FDA Link
01/2021 - 01/2016
6fibroblast growth factor 21IBA
11/2019 - 01/2016
6Adenosine Triphosphate (ATP)IBA
02/2017 - 03/2014
5Cisplatin (Platino)FDA LinkGeneric
09/2021 - 12/2013
5imidazopyridineIBA
01/2020 - 06/2015
5ResveratrolIBA
06/2019 - 08/2015
5Messenger RNA (mRNA)IBA
02/2019 - 01/2010
5Erlotinib Hydrochloride (CP 358,774)FDA Link
01/2019 - 01/2017
5Caspase 3 (Caspase-3)IBA
01/2019 - 04/2015
5Peptides (Polypeptides)IBA
10/2016 - 10/2013
4Fatty Acids (Saturated Fatty Acids)IBA
10/2022 - 01/2017
4Therapeutic UsesIBA
06/2022 - 01/2015
4Mitogen-Activated Protein KinasesIBA
06/2022 - 06/2014
4Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA
11/2021 - 10/2013
4Small Interfering RNA (siRNA)IBA
01/2021 - 11/2015
4GlucocorticoidsIBA
01/2021 - 10/2015
4Fibroblast Growth Factor 1 (FGF-1)IBA
01/2021 - 01/2013
4Biomarkers (Surrogate Marker)IBA
01/2021 - 01/2018
4Thioredoxin Reductase 1IBA
01/2020 - 04/2016
4Type 1 Fibroblast Growth Factor Receptor (Fibroblast Growth Factor Receptor 1)IBA
02/2017 - 04/2015
4Fibroblast Growth Factor 2 (Basic Fibroblast Growth Factor)IBA
03/2016 - 10/2013
3PalmitatesIBA
06/2022 - 02/2015
3NF-kappa B (NF-kB)IBA
06/2022 - 01/2014
3kaempferolIBA
03/2021 - 01/2018
3LDL Lipoproteins (beta Lipoproteins)IBA
01/2021 - 03/2020
3Toll-Like Receptor 2IBA
01/2021 - 12/2020
3Oxidoreductases (Dehydrogenase)IBA
01/2021 - 10/2015
3Nonesterified Fatty Acids (NEFA)IBA
10/2020 - 02/2015

Therapy/Procedure

35Therapeutics
02/2022 - 01/2013
10Oral Administration
01/2022 - 01/2015
6Drug Therapy (Chemotherapy)
02/2020 - 01/2016